What is Orchestrated Oncology?

In biology, every cell needs certain, carefully balanced conditions to thrive. There’s a small army of little protein-based machines in cells that meticulously manage the flow of essential molecules in and out, through their protective membranes. Out with the bad, in with the good. You tip the balance of chemistry one way, the cell dies — the other way, the cell thrives.

We do everything we can to tip the balance in our favor.

The funny thing about cancer cells is that because of the way they evolve in your body, they develop defenses making them like cellular tanks against your own natural immune system.

But they’re not invincible. Certain cell death mechanisms (or pathways) are universal. For example — oxidative stress is a common way to push a cell out of its comfort zone to the point that its cell membranes literally dissolve. Which is why antioxidants (things that block this stress) are generally good for keeping healthy cells thriving. But what if taking antioxidants also protects your cancer when your chemotherapy tries to knock it out?

Pinpointing a disease’s strengths and weaknesses seems like the most obvious way to treat any illness.

What we do

We focus on discovering and researching existing medications and treatments that help disrupt a disease’s defense networks. We design multi-pronged, precision-architected treatment strategies. Strategies that can take out the logistical supply lines of your disease and cause the systemic failure of their protective networks.

If a cell can’t balance its micro-environment, it can’t defend itself, and that makes it vulnerable.

Why now?

Understanding how to target every vulnerability in a biological network is an enormous undertaking. Every cancer type, mutation, or stage is different. They each employ unique strategies to survive in the particular environment they find themselves in. Every target in the network responds differently to different stimuli. Every pathway has multiple interactions with other pathways, and multiple points of failure.

But they all can be targeted if you understand the landscape.

Our platform does the work of entire research teams, gathering more and more data on new, medically sound strategies, and we utilize that data to build smarter, more targeted, precision treatments at scale.

The ability to recruit an army of researchers to answer a particular question used to be limited to large universities and well-funded companies or institutions, and they were generalized, not targeted to individuals. We now have the ability to go out and do precision research, and come back with accurate data in minutes, not months, or even years. When it comes to medical research, we are in the dawn of a new age.

What’s missing is orchestration from mission command

How can we maximize cancer-cell damage while minimizing collateral damage to your healthy cells?

Using advanced multi-agent, adversarial pipelines, we map out these networks and vulnerabilities in a way that is precision-tailored to each patient’s profile, in order to find the best-fit treatment. Are there contraindications? Risks? Can the patient tolerate it in their current condition?

Once we understand what treatments would be effective, we can design a specific plan for each patient’s situation. Can we push cancer cells beyond their safe limits? Lower their defenses? And how can we best keep healthy cells safe? Or clean up the debris after issuing a fatal blow, in order to minimize inflammation?

We manage the what, when to do it, and why, keeping in close collaboration with a patient’s oncologist, and dovetailing our findings with their exact standards of care. Our goal is to maximally disrupt a patient’s cancer through our carefully curated recommendations.

When the dust clears, even the most difficult and treatment-resistant cancers can be shattered with the help of our advanced methodology & workbench software.

Orchestrated Oncology Advancing the state of the art in cancer treatment.